Interim head coach Simon Bassey has the task of pulling off a huge shock as his side are roared on by 8,800 travelling fans in the capital.
Pompey are decimated by suspension, players unavailable and injury for the clash – making how they line up even more fascinating than ever.
1. Josh Griffiths - goalkeeper
Seems to be in the firing line of fans' anger. but firmly established as first choice. Photo: Jason Brown
2. Michael Morrison - right centre back
Going to be key to Pompey's hopes of repelling Spurs' attacking might. Photo: Jason Brown
3. Sean Raggett - centre-back
Just the small task of keeping Engand's captain quite for Raggs... Photo: Jason Brown
4. Connor Ogilive - left centre-back
A heroic performance required from Ogilvie - the kind he's capable of pulling out of the bag. Photo: Jason Brown